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Drug Delivery Systems‐Based Dendrimers and Polymer Micelles for Nuclear Diagnosis and Therapy
Author(s) -
ArandaLara Liliana,
García Blanca Eli Ocampo,
IsaacOlivé Keila,
FerroFlores Guillermina,
MeléndezAlafort Laura,
MoralesAvila Enrique
Publication year - 2021
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.202000362
Subject(s) - dendrimer , nanomedicine , micelle , drug delivery , nanotechnology , nanoparticle , chemistry , surface modification , polymer , imaging agent , materials science , organic chemistry , aqueous solution , microbiology and biotechnology , in vivo , biology
Polymeric nanoparticles encompass micelles and dendrimers. They are used for improving or controlling the action of the loaded therapy or imaging agent, including radionuclides. Some radionuclides possess properties appropriate for simultaneous imaging and therapy of a disease and are therefore called theranostic. The diversity in core materials and surface modification, as well as radiolabeling strategies, offers multiples possibilities for preparing polymeric nanoparticles using radionuclides. The present review describes different strategies in the preparation of such nanoparticles and their applications in nuclear nanomedicine.