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Bioprinting of Collagen: Considerations, Potentials, and Applications
Author(s) -
Lee Jia Min,
Suen Sean Kang Qiang,
Ng Wei Long,
Ma Wai Cheung,
Yeong Wai Yee
Publication year - 2021
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.202000280
Subject(s) - extracellular matrix , tissue engineering , nanotechnology , 3d printing , type i collagen , chemistry , computer science , materials science , biomedical engineering , engineering , biochemistry , composite material , pathology , medicine
Collagen is the most abundant extracellular matrix protein that is widely used in tissue engineering (TE). There is little research done on printing pure collagen. To understand the bottlenecks in printing pure collagen, it is imperative to understand collagen from a bottom‐up approach. Here it is aimed to provide a comprehensive overview of collagen printing, where collagen assembly in vivo and the various sources of collagen available for TE application are first understood. Next, the current printing technologies and strategy for printing collagen‐based materials are highlighted. Considerations and key challenges faced in collagen printing are identified. Finally, the key research areas that would enhance the functionality of printed collagen are presented.