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Selective Adhesion and Directional Migration of Endothelial Cells Guided by Cys‐Ala‐Gly Peptide Density Gradient on Antifouling Polymer Brushes
Author(s) -
Du Wang,
Gao Changyou
Publication year - 2019
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201970028
Subject(s) - adhesion , glycidyl methacrylate , cell adhesion , chemistry , peptide , methacrylate , biophysics , biofouling , polymer , cell migration , polymer chemistry , cell , membrane , biochemistry , polymerization , organic chemistry , biology
Front Cover : The density gradient of CAG peptides is prepared on the cell‐resisting poly (2‐hydroxyethyl methacrylate‐co‐glycidyl methacrylate) brushes in a complementary gradient solution of CAG and mPEG‐SH. The interplay between specific CAG‐endothelial cell affinity and universal resisting to other cells achieves the selective and gradient adhesion and directional migration of ECs, whereas restricts the adhesion of competitive smooth muscle cells. This is reported by Wang Du and Changyou Gao in article 1900292.