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Emulsion Techniques for the Production of Pharmacological Nanoparticles
Author(s) -
Jenjob Ratchapol,
Phakkeeree Treethip,
Seidi Farzad,
Theerasilp Man,
Crespy Daniel
Publication year - 2019
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201900063
Subject(s) - miniemulsion , emulsion polymerization , nanoparticle , emulsion , nanotechnology , microemulsion , polymerization , drug delivery , polymer , materials science , particle size , chemical engineering , chemistry , organic chemistry , pulmonary surfactant , engineering
Nanoparticles have the advantages over micron‐sized particles to typically provide higher intracellular uptake and drug bioavailability. Emulsion techniques are commonly used methods for producing nanoparticles aiming at high encapsulation efficiency, high stability, and low toxicity. Here, the recent developments of nanoparticles prepared from emulsions, the synthesis of nanoparticles, their physicochemical properties, and their biomedical applications are discussed. Selection of techniques, such as emulsion polymerization, miniemulsion polymerization, microemulsion polymerization, and emulsion‐solvent evaporation processes, strongly influences morphologies, size distributions, and particle properties. Details in the synthetic strategies governing the performance of nanoparticles in bioimaging, biosensing, and drug delivery are presented. Benefits and limitations of molecular imaging techniques are also discussed.

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