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Cover Picture: Macromol. Biosci. 7/2015
Author(s) -
Tomov Martin L.,
Olmsted Zachary T.,
Paluh Janet L.
Publication year - 2015
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201570022
Subject(s) - polydimethylsiloxane , embryoid body , cover (algebra) , front cover , induced pluripotent stem cell , nanotechnology , chemistry , materials science , embryonic stem cell , biochemistry , mechanical engineering , engineering , gene
Front Cover: On page 892 M. L. Tomov, Z. T. Olmsted, and J. L. Paluh present complex multicystic structures as revealed by Hoechst staining of a human pluripotent stem cell embryoid body (WA09 EB) of 500 micrometer diameter. Self‐assembly of three cyst types occurs at this large diameter independent of the method of EB formation by single cells or mechanically passaged multicell intermediates. Uniform EBs are generated in high throughput lithography templated polydimethylsiloxane microarrays followed by lineage commitment in adherent cultures.