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Mold‐Based Application of Laser‐Induced Periodic Surface Structures (LIPSS) on Biomaterials for Nanoscale Patterning
Author(s) -
Hendrikson Wim,
MasmanBakker Wendy,
van Bochove Bas,
Skolski Johann,
Eichstädt Justus,
Koopman Bart,
van Blitterswijk Clemens,
Grijpma Dirk,
Römer Gertwillem,
Moroni Lorenzo,
Rouwkema Jeroen
Publication year - 2016
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201500270
Subject(s) - materials science , nanoscopic scale , nanotechnology , polymer , surface modification , laser , surface energy , mold , composite material , chemical engineering , optics , physics , engineering
Laser‐induced periodic surface structures (LIPSS) are highly regular, but at the same time contain a certain level of disorder. The application of LIPSS is a promising method to functionalize biomaterials. However, the absorption of laser energy of most polymer biomaterials is insufficient for the direct application of LIPSS. Here, we report the application of LIPSS to relevant biomaterials using a two‐step approach. First, LIPSS are fabricated on a stainless steel surface. Then, the structures are replicated onto biomaterials using the steel as a mold. Results show that LIPSS can be transferred successfully using this approach, and that human mesenchymal stromal cells respond to the transferred structures. With this approach, the range of biomaterials that can be supplied with LIPSS increases dramatically.

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