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New Semi‐Biodegradable Materials from Semi‐Interpenetrated Networks of Poly(ϵ‐caprolactone) and Poly(ethyl acrylate)
Author(s) -
Lozano Picazo P.,
Pérez Garnes M.,
Martínez Ramos C.,
VallésLluch A.,
Monleón Pradas M.
Publication year - 2015
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201400331
Subject(s) - caprolactone , ethyl acrylate , elastomer , polymer chemistry , materials science , acrylate , copolymer , chemistry , chemical engineering , polymer , composite material , engineering
Semi‐degradable materials may have many applications. Here poly(ethyl acrylate) and poly(ϵ‐caprolactone) were combined as semi‐interpenetrated networks, and thoroughly characterized in terms of final composition, interactions between components, wettability, and mechanical properties. PCL modulates the mechanical properties of the PEA elastomeric network. Cultures of fibroblasts and adipose‐tissue derived stem cells showed excellent biological performance of the materials. The results are relevant for applications seeking materials leaving a permanent supporting skeleton after the partial degradation, as in patches for cardiac regeneration or in abdominal wall meshes.