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Electrostatically Driven Complexation of Liposomes with a Star‐ S haped Polyelectrolyte to Low‐ T oxicity Multi‐ L iposomal Assemblies
Author(s) -
Yaroslavov Alexander A.,
Sybachin Andrey V.,
Zaborova Olga V.,
Pergushov Dmitry V.,
Zezin Alexander B.,
MelikNubarov Nikolay S.,
Plamper Felix A.,
Müller Axel H. E.,
Menger Frederic M.
Publication year - 2014
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201300436
Subject(s) - liposome , polyelectrolyte , cationic polymerization , chemistry , cationic liposome , chemical engineering , polymer chemistry , biophysics , polymer , organic chemistry , biochemistry , genetic enhancement , engineering , gene , biology
Anionic liposomes are electrostatically complexed to a star‐shaped cationic polyelectrolyte. Upon complexation, the liposomes retain their integrity and the resulting liposome‐star complexes do not dissociate in a physiological solution with 0.15 M NaCl. This provides a multi‐liposomal container for possible use as a high‐capacity carrier.