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Generation of Cellular Micropatterns on a Single‐ L ayered Graphene Film
Author(s) -
Hong Daewha,
Bae KiEun,
Yoo Sangjin,
Kang Kyungtae,
Jang Byoungwook,
Kim Jinkyu,
Kim Sehun,
Jeon Seokwoo,
Nam Yoonkey,
Kim YangGyun,
Choi Insung S.
Publication year - 2014
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201300346
Subject(s) - ethylene glycol , methacrylate , polymerization , polymer chemistry , azide , microcontact printing , graphene , grafting , substrate (aquarium) , chemical engineering , materials science , chemistry , nanotechnology , organic chemistry , polymer , oceanography , geology , engineering
Micropatterns of fibroblast and hippocampal neurons are generated on a single‐layered graphene substrate. A large‐area (1 cm × 1 cm) graphene film on Si/SiO 2 is functionalized by surface‐initiated ATRP of non‐biofouling oligo(ethylene glycol) methacrylate, after grafting of the polymerization initiator bearing α‐bromoisobutylate via photoreaction of the perfluorophenyl azide group. The microcontact printing‐assisted spatio‐selective reaction, after chemical activation of the terminal hydroxyl group of oligo(ethylene glycol) in the polymeric film, is utilized to generate the patterns of fibroblast and hippocampal neurons.