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Functionalization of Polycarbonate Surfaces by Grafting PEG and Zwitterionic Polymers with a Multicomb Structure
Author(s) -
Yang Jing,
Lv Juan,
Behl Marc,
Lendlein Andreas,
Yang Dazhi,
Zhang Li,
Shi Changcan,
Guo Jintang,
Feng Yakai
Publication year - 2013
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201300264
Subject(s) - surface modification , polycarbonate , grafting , peg ratio , polymer , polymer chemistry , chemistry , chemical engineering , chemical modification , polymer science , organic chemistry , finance , engineering , economics
The hemocompatibility of polycarbonateurethane (PCU) surfaces is improved by decoration with poly(poly(ethylene glycol) methacrylate) (poly(PEGMA)) and zwitterionic poly(3‐((2‐(methacryloyloxy)ethyl)dimethylammonio)propane‐1‐sulfonate) (poly(DMAPS)) blocks providing a novel multicomb structure obtained by application of surface‐initiated atom transfer radical polymerization (s‐ATRP) conditions. The PCU‐poly(PEGMA‐ g ‐DMAPS) surface shows high hydrophilicity with a low contact angle of 20.6 ± 1.8°, while PCU‐poly(PEGMA‐ b ‐DMAPS) surface exhibitsed a contact angle of 30.5 ± 2.6°. Furthermore, PCU‐poly(PEGMA‐ g ‐DMAPS) surface shows very low platelet adsorption indicating that multicomb structure modified PCUs are preferred candidate materials for blood‐contacting materials.