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Preparation of Biocompatible Aggregation‐ I nduced Emission Homopolymeric Nanoparticles for Cell Imaging
Author(s) -
Ma Chunping,
Ling Qingqing,
Xu Shidang,
Zhu Hongni,
Zhang Ge,
Zhou Xie,
Chi Zhenguo,
Liu Siwei,
Zhang Yi,
Xu Jiarui
Publication year - 2014
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201300259
Subject(s) - raft , polymer , nanoparticle , biocompatibility , polymerization , polymer chemistry , chemistry , chain transfer , tetrahydrofuran , reversible addition−fragmentation chain transfer polymerization , chemical engineering , fragmentation (computing) , radical polymerization , materials science , organic chemistry , nanotechnology , solvent , engineering , computer science , operating system
A series of new homopolymers with various degrees of polymerization derived from vinyl tetraphenylethene, that is, poly[2‐(4‐vinylphenyl)ethene‐1,1,2‐triyl)tribenzene] homopolymers, is synthesized by reversible addition–fragmentation chain transfer (RAFT) polymerization. The homopolymers exhibit a significant aggregation‐induced emission (AIE) effect and an ability to assemble themselves into AIE polymer nanoparticles (NPs) during precipitation in a water/tetrahydrofuran (THF) mixture. The NPs also exhibit good dispersibility, stability, and biocompatibility. The AIE polymer NPs are used in imaging studies of HeLa cells.