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Hybrid POSS‐Containing Brush on Gold Surfaces for Protein Resistance
Author(s) -
Ye Xiaolu,
Gong Junbo,
Wang Zhongping,
Zhang Zengming,
Han Sheng,
Jiang Xuesong
Publication year - 2013
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201200461
Subject(s) - ethylene glycol , peg ratio , polymer , protein adsorption , brush , chemical engineering , adsorption , polymer chemistry , materials science , polymer brush , surface modification , chemistry , composite material , organic chemistry , polymerization , finance , engineering , economics
A hybrid polymer brush containing poly(ethylene glycol) (PEG) chains and polyhedral oligosilsesquioxane (POSS) on a gold surface is presented that exhibits an excellent protein resistance and long‐term stability. A series of hybrid polymer brushes with different length and numbers of PEG chains are fabricated through chemisorption of PEG‐POSS‐SH on the gold surface. Protein adsorption of these hybrid brushes is investigated. The amount of protein adsorption decreases with increasing lengths and numbers of PEG chains. After immersion in BSA solution for two months, the PPS4 brushes retain their protein resistance, while a PEG‐SH layer loses its non‐fouling performance. These POSS‐containing hybrid polymer brushes might offer an alternative for modification of gold surface with an excellent protein resistance for long‐term applications.