Premium
Nano‐hydroxyapatite Surfaces Grafted with Electroactive Aniline Tetramers for Bone‐Tissue Engineering
Author(s) -
Liu Yadong,
Cui Haitao,
Zhuang Xiuli,
Zhang Peibiao,
Cui Yi,
Wang Xianhong,
Wei Yen,
Chen Xuesi
Publication year - 2013
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201200345
Subject(s) - thermogravimetric analysis , fourier transform infrared spectroscopy , biocompatibility , x ray photoelectron spectroscopy , nanoparticle , aniline , scanning electron microscope , chemical engineering , covalent bond , chemistry , polymer chemistry , grafting , nuclear chemistry , adhesion , materials science , nanotechnology , polymer , organic chemistry , composite material , engineering
An electroactive amino/carboxyl‐capped aniline tetramer (AT) is covalently grafted to the surface of hydroxyapatite (HA) nanoparticles to generate novel electroactive HA‐AT nanoparticles. The amount of AT ranges from 16.5 to 34.0 wt% and is characterized by thermogravimetric analysis (TGA). The HA‐AT nanoparticles are characterized by Fourier transform IR (FTIR) spectroscopy, X‐ray photoelectron spectroscopy (XPS), X‐ray diffraction, and scanning electron microscopy (SEM). For the excellent electroactivity of HA‐AT, the mixture of HA‐AT and PLA shows much better adhesion ability and proliferation ability than that of HA and a PLA matrix. At a 15 wt% AT grafting amount, the matrix shows the best biocompatibility.