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Fluorescent Polymeric Micelles with Tetraphenylethylene Moieties and Their Application for the Selective Detection of Glucose
Author(s) -
Shen Xiang,
Shi Yi,
Peng Bo,
Li Kan,
Xiang Junfeng,
Zhang Guanxin,
Liu Zitong,
Chen Yongming,
Zhang Deqing
Publication year - 2012
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201200261
Subject(s) - micelle , chemistry , fluorescence , tetraphenylethylene , amphiphile , aqueous solution , bovine serum albumin , copolymer , ascorbic acid , photochemistry , organic chemistry , polymer chemistry , combinatorial chemistry , polymer , chromatography , aggregation induced emission , physics , food science , quantum mechanics
By linking TPE moieties that exhibit aggregation‐induced (enhanced) emission to the amphiphilic copolymer 1 , fluorescent micelles are prepared and characterized. The polymeric micelles exhibit relatively strong fluorescence which can be tuned by heating and cooling. By combining cascaded enzymatic (oxidation of D ‐glucose with GOx) and chemical (oxidation of I – by H 2 O 2 ) reactions, the fluorescent micelles of copolymer 1 are successfully utilized for the selective detection of D ‐glucose in aqueous solution. The influences of proteins (e.g., bovine serum albumin) and reductants (e.g., ascorbic acid) on this fluorescence detection of D ‐glucose are also discussed.