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Biocompatible Poly( L ‐lactide)/MWCNT Nanocomposites: Morphological Characterization, Electrical Properties, and Stem Cell Interaction
Author(s) -
Lizundia Erlantz,
Sarasua Jòsè Ramon,
D'Angelo Francesco,
Orlacchio Aldo,
Martino Sabata,
Kenny Josè Maria,
Armentano Ilaria
Publication year - 2012
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201200008
Subject(s) - nanocomposite , carbon nanotube , materials science , percolation threshold , percolation (cognitive psychology) , tissue engineering , characterization (materials science) , biocompatible material , nanotube , nanotechnology , nanoparticle , composite material , chemical engineering , electrical resistivity and conductivity , biomedical engineering , electrical engineering , biology , engineering , medicine , neuroscience
The promising perspectives of PLLA‐based nanostructured biomaterials and their relevance in tissue engineering are reported. Nanocomposites based on PLLA and MWCNTs are developed with an MWCNT content ranging from 0 to 3 wt%. The electrical properties show a percolation threshold within a range of 0.21–0.33 wt% MWCNTs, and the conductivity increases by six orders of magnitude. The surface structure shows changes with the carbon nanotube concentration. The functional role of MWCNTs incorporation in terms of interactions with adult stem cells suggests that PLLA/MWCNT nanocomposites are suitable substrates for primary stem cell culture.