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Macromol. Biosci. 6/2011
Author(s) -
Lee Min Sang,
Jang Yeon Lim,
Huynh Dai Phu,
Huynh Cong Truc,
Lee Yuhan,
Chae Su Young,
Kim Sun Hwa,
Park Tae Gwan,
Lee Doo Sung,
Jeong Ji Hoon
Publication year - 2011
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201190016
Subject(s) - deprotonation , polyelectrolyte , protonation , plasmid , copolymer , dna , chemistry , cover (algebra) , polymer chemistry , stereochemistry , polymer science , biochemistry , organic chemistry , polymer , engineering , mechanical engineering , ion
Cover: In a mildly acidic environment (pH 5.4), the shown pentablock copolymer is protonated and able to interact with plasmid DNA to form polyelectrolyte complexes. Subsequent transition to the physiological pH causes deprotonation of the PAE blocks, leading to the formation of nanosized capsular structures encapsulating plasmid DNA. Further details can be found in the article by M. S. Lee, Y. L. Jang, D. P. Huynh, C. T. Huynh, Y. Lee, S. Y. Chae, S. H. Kim, T. G. Park, D. S. Lee, * and J. H. Jeong * on page 789 .