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Bacterial Adhesion‐Resistant Poly(2‐hydroxyethyl methacrylate) Derivative for Mammalian Cell Cultures
Author(s) -
Sohn EunHo,
Ahn Jooyeon,
Bhang Suk Ho,
Kang Junil,
Yoon Jeyong,
Kim ByungSoo,
Lee JongChan
Publication year - 2012
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201100235
Subject(s) - methacrylate , biofouling , chemistry , polymer , cytotoxicity , 2 hydroxyethyl methacrylate , cell adhesion , adhesion , polymer chemistry , cell culture , biophysics , polymerization , organic chemistry , in vitro , biochemistry , membrane , biology , genetics
In an attempting to find new biomaterials for mammalian cell culture, PHEMA derivatives with ester side groups are synthesized by one‐step polymer‐analogous reaction. These polymers show excellent antifouling properties against S. epidermidis and P. aeruginosa while their cytotoxicity and proliferation activity for HDF cell are on a similar level as commercially available TCPS. The interesting bioadhesion property is systematically correlated with surface properties of the PHEMA derivatives.