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Macromol. Biosci. 7/2010
Author(s) -
Zhao Huaying,
Brown Patrick H.,
Balbo Andrea,
FernándezAlonso María del Carmen,
Polishchuck Natasha,
Chaudhry Charu,
Mayer Mark L.,
Ghirlando Rodolfo,
Schuck Peter
Publication year - 2010
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201090013
Subject(s) - macromolecule , analytical ultracentrifugation , cover (algebra) , polymer science , chemistry , analytical chemistry (journal) , ultracentrifuge , chromatography , engineering , mechanical engineering , biochemistry
Back Cover: The image displays Svedberg's analytical centrifuge along with a recent development in analytical ultracentrifugation (AUC), a new computational model for the analysis of macromolecules in sedimentation velocity. The plot shows macromolecular concentration profiles superimposed by solvent signals, such as those arising from optically mismatched small co‐solutes. The macromolecular boundaries appear obscure and twisted due to the buffer signal and are not interpretable using traditional analysis. The new model accounts simultaneously for macromolecular and small co‐solvent concentration distributions. Further details can be found in the full paper by H. Zhao, * P. H. Brown, A. Balbo, M. d. C. F. Alonso, N. Polishchuck, C. Chaudhry, M. L. Mayer, R. Ghirlando, and P. Schuck on page 736 . Photograph is courtesy of Curt Ekström, The Svedberg Laboratory.