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Polymer/Bacteria Composite Nanofiber Nonwovens by Electrospinning of Living Bacteria Protected by Hydrogel Microparticles
Author(s) -
Gensheimer Marco,
BrandisHeep Astrid,
Agarwal Seema,
Thauer Rudolf K.,
Greiner Andreas
Publication year - 2011
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.201000310
Subject(s) - electrospinning , nanofiber , bacteria , polymer , chemical engineering , composite number , chemistry , materials science , polymer chemistry , nanotechnology , composite material , genetics , biology , engineering
Physically crosslinked PVA‐hydrogel microparticles are utilized for encapsulation of E. coli and M. luteus . The bacteria survive dry storage or treatment with bacteria‐hostile organic solvents significantly better than unprotected bacteria as proven by culture‐test experiments. The bacteria‐protecting PVA microparticles are available for standard polymer‐solution‐processing techniques, as exemplarily shown by co‐electrospinning of living bacteria encapsulated in dry PVA‐hydrogel microparticles together with PVB‐, PLLA‐, and PCL‐form organic solvents.