Premium
Biodegradable Multiblock Copolymers Based on Oligodepsipeptides with Shape‐Memory Properties
Author(s) -
Feng Yakai,
Behl Marc,
Kelch Steffen,
Lendlein Andreas
Publication year - 2009
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.200800199
Subject(s) - copolymer , hydrolytic degradation , materials science , thermoplastic elastomer , thermoplastic , brittleness , shape memory alloy , composite material , diol , polymer chemistry , hydrolysis , deformation (meteorology) , polymer , chemistry , organic chemistry
Thermoplastic phase‐segregated multiblock copolymers with polydepsipeptides and PCL segments were prepared via coupling of diol and PCL‐diol using an aliphatic diisocyanate. The obtained multiblock copolymers showed good elastic properties and a shape memory. Almost complete fixation of the mechanical deformation, resulting in quantitative recovery of the permanent shape with a switching temperature around body temperature, was observed. In hydrolytic degradation experiments, a quick decrease of the molecular weight without induction period was observed, and the material changed from elastic to brittle in 21 d. These materials promise a high potential for biomedical applications such as smart implants or medical devices.