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Rationally Designing Molecularly Imprinted Polymer towards Predetermined High Selectivity by Using Metal as Assembled Pivot
Author(s) -
Li Songjun,
Liao Cong,
Li Wuke,
Chen Yifeng,
Hao Xiao
Publication year - 2007
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.200700047
Subject(s) - molecularly imprinted polymer , template , selectivity , polymer , naproxen , chemistry , combinatorial chemistry , monomer , enantiomer , molecular imprinting , molecular recognition , adsorption , nanotechnology , materials science , molecule , organic chemistry , catalysis , medicine , alternative medicine , pathology
This article presents an original work aiming at rationally designing a molecularly imprinted polymer (MIP) towards high selective recognition. Assembled with ( S )‐naproxen as a template and 4‐vinylpyridine as a functional monomer, a certain amount of cobalt, as pivot, is added for the preparation of MIP. The result indicates that the use of pivot plays obviously a positive role in increasing the specificity of MIP, so as to adsorb more for the template and less for its enantiomer. Related information indicates that this, in logic, can be a result of increasing match between binding sites and the templates, which makes the polymer capable of selectively recognizing the imprint species.