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Interface Interactions of Osteoblasts with Structured Titanium and the Correlation between Physicochemical Characteristics and Cell Biological Parameters
Author(s) -
Nebe J. G. Barbara,
Luethen Frank,
Lange Regina,
Beck Ulrich
Publication year - 2007
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.200600293
Subject(s) - titanium , biomaterial , polishing , corundum , titanium alloy , adhesion , surface finish , chemistry , surface roughness , materials science , chemical engineering , composite material , mineralogy , nanotechnology , metallurgy , alloy , engineering
Cellular behavior at the interface of an implant is influenced by the material's topography. However, little is known about the correlation between the biological parameters and the physicochemical characteristics of the biomaterial. We therefore modified pure titanium surfaces by polishing, machining, blasting with glass spheres, blasting with corundum particles, and vacuum plasma spraying to give progressively higher surface roughness. The material surface was characterized by SEM, surface profiling, and electrochemical methods. We revealed a correlation for integrin expression and formation, adhesion, spreading, proliferation, and bone sialo protein expression with the physicochemical parameters of the titanium surfaces.