Premium
Cover Picture: Macromol. Biosci. 4/2005
Author(s) -
Ouhib Farid,
Randriamahefa Solo,
Wintgens Véronique,
Guérin Philippe,
Barbaud Christel
Publication year - 2005
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.200590006
Subject(s) - pyrene , amphiphile , micelle , nanoparticle , copolyester , fluorescence , materials science , copolymer , nanotechnology , chemistry , polymer science , organic chemistry , optics , polymer , physics , aqueous solution , polyester
Cover: The Figure shows the structure of novel biodegradable block and statistical copolyesters composed of hydrophilic (( R,S )‐3,3‐dimethylmalic acid) and hydrophobic (hexyl ( R,S )‐3,3‐dimethylmalate) repetitive units. These novel materials display amphiphilic properties and form micelles and nanoparticles usable as potential drug delivery system. Transmission electron microphotography shows regular spherical nanoparticles with mean size suitable for target molecules encapsulation. Micelles are characterized by the critical aggregation concentration determined by the plot of the ratio of two vibrational bands of pyrene (used as fluorescence probe) versus the concentration of the block copolyester. Further details can be found in the Full Paper by F. Ouhib, S. Randriamahefa, V. Wintgens, P. Guérin, and C. Barbaud on Page 299.