Premium
Novel Biodegradable and Thermosensitive Dex‐AI/PNIPAAm Hydrogel
Author(s) -
Zhang XianZheng,
Wu DaQing,
Sun GuoMing,
Chu ChihChang
Publication year - 2003
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.200390014
Subject(s) - lower critical solution temperature , self healing hydrogels , dextran , copolymer , poly(n isopropylacrylamide) , isocyanate , moiety , chemistry , polymer chemistry , chemical engineering , materials science , polymer , polyurethane , organic chemistry , engineering
The dextran‐allyl isocyanate/poly( N ‐isopropylacrylamide) (Dex‐AI/PNIPAAm) hydrogel was designed and prepared by copolymerization of the modified dextran with N ‐isopropylacrylamide (NIPAAm). This novel Dex‐AI/PNIPAAm hydrogel is biodegradable and intelligent due to its biodegradable dextran linkage and thermosensitive PNIPAAm moiety. With an increase in dextran content, it exhibits the increased lower critical solution temperature (LCST) and decreased porous microstructure. Also, the thermosensitivity of this hydrogel is also controllable and adjustable depending on the different compositions.SEM micrographs of the Dex‐AI/PNIPAAm hydrogels.