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Synthesis and Characterization of Chitosan Grafted Oligo( L ‐lactic acid)
Author(s) -
Yao Fanglian,
Liu Chang,
Chen Wei,
Bai Yun,
Tang Zhiyuan,
Yao Kangde
Publication year - 2003
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.200350035
Subject(s) - chitosan , lactic acid , chemistry , copolymer , polymer chemistry , grafting , molecular mass , acetic acid , organic chemistry , polymer , bacteria , enzyme , genetics , biology
Chitosan grafted oligo( L ‐lactic acid) copolymers with different length of side chain were prepared through the reaction of terminal aldehyde group of oligo( L ‐lactic acid) (OLLA) and amino groups of chitosan. The mean molecular mass of the grafting OLLA chain was ca. 600 ∼ 5 000. The graft copolymers are soluble in DMSO, DMF and acetic acid. The synthesis method and structure described here provide chitosan‐ g ‐OLLA copolymers with broad applicability.Structure of chitosan‐ g ‐oligo( L ‐lactic acid).