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Primary Biliary Cholangitis Guidance Update: Implications for Liver Transplantation
Author(s) -
Levy Cynthia
Publication year - 2018
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.25321
Subject(s) - miami , medicine , liver transplantation , waiting list , suite , reprint , transplantation , general surgery , environmental science , archaeology , soil science , history , physics , astronomy
Although primary biliary cholangitis (PBC) remains an important indication for liver transplantation (LT), it provides an example where successful medical therapy alters the natural history of the disease, with use of ursodeoxycholic acid (UCDA) leading to improved transplant-free survival (1).The number of patients listed for liver transplant for PBC has declined by nearly 50% in the United States and United Kingdom. The female:male ratio has been decreasing in transplant waiting lists, and blacks and Hispanics are underrepresented (2). When non-white patients are listed, they are usually younger and with higher severity scores compared with white patients. In another study, Hispanics had the highest percentage of wait-list mortality (20.8%) compared with other races and ethnicities and were less likely to actually receive the liver transplant (3). This article is protected by copyright. All rights reserved.