Premium
Updated Hepatitis B Guidance: Implications for liver transplant patients
Author(s) -
Verna Elizabeth C.
Publication year - 2018
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.25037
Subject(s) - medicine , liver transplantation , liver disease , transplantation , hepatitis b , family medicine , reprint , physics , astronomy
Despite significant strides in hepatitis B virus (HBV) vaccination and prevention in the United States and throughout the world, liver transplantation remains the only curative option for patients with complications of chronic HBV, including severely decompensated cirrhosis, hepatocellular carcinoma (HCC), and severe acute presentations including acute liver failure. The recently published 2018 American Association for the Study of Liver Diseases (AASLD) Hepatitis B Guidance provides an evidence-based approach to screening, prevention, diagnosis, and clinical management of patients with HBV. In contrast to the 2016 HBV guideline and meta-analysis, this guidance document also incorporates expert consensus along with formal review of the published literature and the World Health Organization guidance on HBV. Thus, this guidance document provides a crucial synthesis of information to guide practitioners in the care of patients with HBV. However, given the limited data available for HBV management specifically for liver transplant candidates and recipients, there is a lack of high-quality evidence in many aspects of the care of these most complex patients. Liver Transplantation for HBV-Related End-Stage Liver Disease