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Microbiota and the liver
Author(s) -
Shen TingChin David,
Pyrsopoulos Nikolaos,
Rustgi Vinod K.
Publication year - 2018
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.25008
Subject(s) - medicine , liver transplantation , dysbiosis , cirrhosis , nonalcoholic fatty liver disease , alcoholic liver disease , nonalcoholic steatohepatitis , microbiome , liver disease , fatty liver , steatohepatitis , fecal bacteriotherapy , disease , gastroenterology , immunology , transplantation , bioinformatics , microbiology and biotechnology , antibiotics , biology , clostridium difficile
The gut microbiome outnumbers the human genome by 150‐fold and plays important roles in metabolism, immune system education, tolerance development, and prevention of pathogen colonization. Dysbiosis has been associated with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and alcoholic liver disease (ALD) as well as cirrhosis and complications. This article provides an overview of this relationship. Liver Transplantation 24 539–550 2018 AASLD.