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Longterm health‐related quality of life after living liver donation
Author(s) -
Humphreville Vanessa R.,
Radosevich David M.,
Humar Abhinav,
Payne William D.,
Kandaswamy Raja,
Lake John R.,
Matas Arthur J.,
Pruett Timothy L.,
Chinnakotla Srinath
Publication year - 2016
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.24304
Subject(s) - medicine , vitality , donation , quality of life (healthcare) , liver transplantation , sf 36 , population , mental health , gerontology , surgery , transplantation , health related quality of life , environmental health , psychiatry , philosophy , theology , nursing , disease , economics , economic growth
There are little data on longterm outcomes, health‐related quality of life (HRQoL), and issues related to living donor right hepatectomy specifically. We studied longterm HRQoL in 127 living liver donors. A donor‐specific survey (DSS) was used to evaluate the living liver donor morbidity, and the 36‐item short‐form health survey (short‐form 36 health survey, version 1 [SF‐36]) was used to assess generic outcomes. The DSS was completed by 107 (84.3%) donors and the SF‐36 by 62 (49%) donors. Median follow‐up was 6.9 years. Of the 107 donors, 12 (11.2%) donors reported their health as better, whereas 84 (78.5%) reported their health the same as before donation. Ninety‐seven (90.7%) are currently employed. The most common postdonation symptom was incisional discomfort (34%). Twenty‐four donors (22.4%) self‐reported depression symptoms after donation. Ninety‐eight (91.6%) rated their satisfaction with the donation process ≥ 8 (scale of 1‐10). Three factors—increased vitality (correlation, 0.44), decreased pain (correlation, 0.34), and a recipient who was living (correlation, 0.44)—were independently related to satisfaction with the donor experience. Vitality showed the strongest association with satisfaction with the donor experience. Mental and physical component summary scale scores for donors were statistically higher compared to the US population norm ( P < 0.001). Donors reported a high satisfaction rate with the donation process, and almost all donors (n = 104, 97.2%) would donate again independent of experiencing complications. Our study suggests that over a longterm period, liver donors continue to have above average HRQoL compared to the general population. Liver Transpl 22:53‐62, 2016 . © 2015 AASLD.