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Recipient factors associated with having a potential living donor for liver transplantation
Author(s) -
Doyle Adam,
Rabie Rania N.,
Mokhtari Arastoo,
Cattral Mark,
Ghanekar Anand,
Grant David,
Greig Paul,
Levy Gary,
Lilly Leslie,
McGilvray Ian,
Selzner Markus,
Selzner Nazia,
Renner Eberhard L.
Publication year - 2015
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.24148
Subject(s) - medicine , donation , liver transplantation , socioeconomic status , transplantation , volunteer , liver disease , logistic regression , odds ratio , psychological intervention , multivariate analysis , cohort , united network for organ sharing , living donor liver transplantation , gerontology , population , environmental health , psychiatry , agronomy , economics , biology , economic growth
Because of a persistent discrepancy between the demand for liver transplantation (LT) and the supply of deceased donor organs, there is an interest in increasing living donation rates at centers trained in this method of transplantation. We examined a large socioeconomically heterogeneous cohort of patients listed for LT to identify recipient factors associated with living donation. We retrospectively reviewed 491 consecutive patients who were listed for LT at our center over a 24‐month period. Demographic, medical, and socioeconomic data were extracted from electronic records and compared between those who had a potential living donor (LD) volunteer for assessment and those who did not; 245 patients (50%) had at least 1 potential LD volunteer for assessment. Multivariate logistic regression analysis identified that patients with a LD were more likely to have Child‐Pugh C disease (odds ratio [OR], 2.44; P = 0.02), and less likely to be older (OR, 0.96; P = 0.002), single (OR, 0.34; P = 0.006), divorced (OR, 0.53; P = 0.03), immigrants (OR, 0.38; P = 0.049), or from the lowest income quintile (OR, 0.44; P = 0.02). In conclusion, this analysis has identified several factors associated with access to living donation. More research is warranted to define and overcome barriers to living donor liver transplantation through targeted interventions in underrepresented populations. Liver Transpl 21:897‐903, 2015 . © 2015 AASLD.