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Present state of immunosuppressive therapy in liver transplant recipients
Author(s) -
Wiesner Russell H.,
Fung John J.
Publication year - 2011
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.22410
Subject(s) - medicine , immunosuppression , liver transplantation , immunosuppressive drug , immunology , intensive care medicine , transplantation
Key Points 1. Our increasing understanding of the signaling pathways and cellular interactions in transplant immunobiology has facilitated targeted strategies using novel immunosuppressive agents. 2. The pattern of immunosuppressive drug use in the United States continues to change, and the changes include the use of antibody induction therapy and the agents used in maintenance therapy. 3. The driving forces behind the development of new immunosuppressive regimens are the long‐term complications of current immunosuppressive regimens (particularly renal dysfunction and metabolic disturbances). Liver Transpl, 2011. © 2011 AASLD.