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The failure of immunosuppression withdrawal: Patient benefit is not detectable, inducible, or reproducible
Author(s) -
Porrett Paige,
Shaked Abraham
Publication year - 2011
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.22377
Subject(s) - immunosuppression , medicine , intensive care medicine , nephrotoxicity , liver transplantation , transplantation , kidney
Abstract Key Points (1) Immunosuppression is responsible for excellent patient outcomes. (2) Immunosuppression withdrawal fails in most patients. (3) Patients who may benefit from immunosuppression withdrawal cannot currently be identified. (4) No data suggest that immunosuppression withdrawal decreases patient morbidity (ie, nephrotoxicity). (5) The minimization of immunosuppression instead of withdrawal may be adequate for improving patient outcomes. Liver Transpl, 2011. © 2011 AASLD.