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Transjugular intrahepatic portosystemic shunt for the treatment of sinusoidal obstruction syndrome in a liver transplant recipient and review of the literature
Author(s) -
CamposVarela Isabel,
Castells Lluís,
Dopazo Cristina,
PérezLafuente Mercedes,
Allende Helena,
Len Oscar,
Llopart Lluís,
Vargas Victor,
Charco Ramón
Publication year - 2012
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.22351
Subject(s) - medicine , transjugular intrahepatic portosystemic shunt , liver transplantation , ascites , jaundice , surgery , shunt (medical) , portosystemic shunt , medical therapy , portal hypertension , transplantation , radiology , cirrhosis
Sinusoidal obstruction syndrome (SOS) is a rare, life‐threatening clinical syndrome resulting from sinusoidal congestion, and it is characterized by hepatomegaly, ascites, weight gain, and jaundice. The frequency of this condition after liver transplantation (LT) is low, but when SOS is severe and refractory to medical therapy, the ultimate solution is retransplantation. We describe a patient with SOS after LT who was successfully treated by the placement of a transjugular intrahepatic portosystemic shunt (TIPS). Although information on this approach is scarce because of the low incidence of SOS in LT patients, we review the available literature on treating this condition with a TIPS. On the basis of the reported information and our patient's outcome, we suggest that prompt TIPS placement can be considered for SOS when medical treatment fails. Nonetheless, a formal assessment and prospective studies are needed to confidently indicate TIPS placement in this situation. Liver Transpl 18:201–205, 2012. © 2011 AASLD.