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Retransplantation for donor‐derived neuroendocrine tumor
Author(s) -
Begum Rehana,
Harnois Denise,
Satyanarayana Raj,
Krishna Murli,
Halling Kevin C.,
Kim George P.,
Nguyen Justin H.,
Keaveny Andrew P.
Publication year - 2011
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.22196
Subject(s) - medicine , liver transplantation , neuroendocrine tumors , chemotherapy , transplantation , oncology , surgery
Although tumor transmission through liver transplantation (LT) is a rare occurrence, the consequences can be devastating, even when a very aggressive management approach is adopted. We report the case of a donor‐derived small cell neuroendocrine tumor (NET) in a patient who underwent LT for cholangiocarcinoma. Despite locoregional therapy, chemotherapy and ultimately retransplantation, the patient died from metastases. The high grade nature of the NET was the most important determinant of prognosis in this case. Our experience suggests that retransplantation for donor‐derived NET should only be considered when tumor biology is favorable. Liver Transpl 17:83–87, 2011. © 2011 AASLD.