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Donor‐transmitted diseases
Author(s) -
Teperman Lewis
Publication year - 2010
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.22153
Subject(s) - medicine , malignancy , transmission (telecommunications) , disease , serology , organ donation , liver transplantation , intensive care medicine , transplantation , immunology , surgery , pathology , antibody , electrical engineering , engineering
Key Points 1. Donor‐derived disease transmission occurs in less than 1% of all transplants. 2. Early recognition and screening of the donor are essential to prevent transmission. Nucleic acid testing, though costly, is more sensitive and accurate than serological testing, and when it is used appropriately, it can effectively identify high‐risk donors. 3. Prompt and aggressive treatment of any recipient of donor‐derived disease is essential for patient survival. Early removal of the transplanted organ is often necessary. 4. Some instances of malignancy may be acceptable for organ donation. Liver Transpl 16:S40‐S44, 2010. © 2010 AASLD.