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A report of human herpesvirus 6–associated encephalitis in a solid organ transplant recipient and a review of previously published cases
Author(s) -
Vinnard Christopher,
Barton Todd,
Jerud Elliot,
Blumberg Emily
Publication year - 2009
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.21816
Subject(s) - medicine , organ transplantation , solid organ , encephalitis , human herpesvirus 6 , liver transplantation , virology , intensive care medicine , transplantation , herpesviridae , virus , surgery , viral disease
Human herpesvirus 6 (HHV‐6) is a common pathogen among children, classically presenting as fever and rash that resolve without specific therapy (exanthem subitum or roseola infantum). Also identified as a pathogen in hematopoietic cell transplant and solid organ transplant (SOT) recipients, it has been recognized as a cause of limbic encephalitis, characterized by confusion and amnesia, with magnetic resonance imaging findings of T2 hyperintensity of the amygdala and hippocampus. We report a case of limbic encephalitis associated with HHV‐6 infection in a liver transplant recipient, and we review previously reported cases of HHV‐6 encephalitis in SOT recipients. Liver Transpl 15:1242–1246, 2009. © 2009 AASLD.