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Etiology and prognosis of acute liver failure in children
Author(s) -
Dhawan Anil
Publication year - 2008
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.21641
Subject(s) - etiology , medicine , liver transplantation , encephalopathy , liver failure , hepatic encephalopathy , transplantation , pediatrics , intensive care medicine , hepatitis , cirrhosis
Abstract Key Points1 The etiology of acute liver failure in children differs from that in adults, with metabolic conditions being commoner in Europe and North America and hepatitis A being the commonest cause in Asia and South America. 2 Encephalopathy usually is a late feature and is not essential for the diagnosis. 3 Unlike adults, there are no good prognostic criteria that can predict survival without liver transplantation. 4 It is important to exclude genetic multisystem disorders before liver transplantation is considered.