Transplantation‐mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors | Zendy

Diaz Geraldine C. | Zendy; Prowda Joan | Zendy; Lo Irene J. | Zendy; Arepally Gowthami M. | Zendy; Evans Neal | Zendy; Wheeless Yvonne | Zendy; Samstein Benjamin | Zendy; Guarrera James V. | Zendy; Renz John F. | Zendy

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Transplantation‐mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors

Author(s) -

Diaz Geraldine C.,

Prowda Joan,

Lo Irene J.,

Arepally Gowthami M.,

Evans Neal,

Wheeless Yvonne,

Samstein Benjamin,

Guarrera James V.,

Renz John F.

Publication year - 2008

Publication title -

liver transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.814

H-Index - 150

eISSN - 1527-6473

pISSN - 1527-6465

DOI - 10.1002/lt.21539

Subject(s) - medicine , liver transplantation , transplantation , intensive care medicine , medline , immunology , political science , law

Transplantation‐mediated alloimmune thrombocytopenia (TMAT) is donor‐derived thrombocytopenia following solid‐organ transplantation. To date, no clear consensus on the appropriateness of organ utilization from cadaver donors with a history of idiopathic thrombocytopenia purpura (ITP) has emerged. Herein is reported a devastating case of TMAT following liver transplantation utilizing an allograft from a donor with ITP that resulted in allograft failure. The literature is reviewed in this context to propose preliminary guidelines regarding utilization of allografts from cadaver donors with a history of ITP. Liver Transpl 2008;14:1803–1809. © 2008 AASLD.

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