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Anti‐erythropoietin antibody–mediated pure red cell aplasia in a living donor liver transplant recipient treated for hepatitis C virus
Author(s) -
Schecter Jordan M.,
Mears J. Gregory,
Alobeid Bachir,
Gaglio Paul J.
Publication year - 2007
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.21332
Subject(s) - medicine , ribavirin , pure red cell aplasia , liver transplantation , erythropoietin , hepatitis c virus , transplantation , antibody , gastroenterology , hepatitis c , immunology , virus , anemia
After liver transplantation, reinfection of the newly engrafted liver with hepatitis C virus is essentially universal in patients who are viremic at the time of transplantation. Treatment with interferon preparations with or without ribavirin is recommended in patients with marked histologic injury; however, hematologic toxicity associated with therapy has been reported, which is usually treated with growth factor support, including erythropoietin analogues. We present the first reported case of anti‐erythropoietin antibody–mediated pure red cell aplasia arising in the setting of hepatitis C virus therapy in a patient who underwent living donor liver transplantation. Liver Transpt 13: 1589–1592. 2007. © 2007 AASLD.