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Guillain‐Barré syndrome triggered by influenza vaccination in a recipient of liver transplant on FK506
Author(s) -
Moon JoonShik,
Souayah Nizar
Publication year - 2006
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.20864
Subject(s) - medicine , liver transplantation , tacrolimus , guillain barre syndrome , complication , immunology , vaccination , liver dysfunction , antibody , transplantation , gastroenterology
Abstract Guillain‐Barré syndrome (GBS) has been rarely reported after liver transplantation and generally has good outcome. We report a liver transplant patient on FK506 (tacrolimus) who developed GBS 6 months after liver transplantation. There was no evidence of liver rejection or active infection. Despite treatment with intravenous immunoglobulin, the patient expired. GBS occurred despite downregulation of T cells by FK506, suggesting that humoral dysfunction might be the predominant mechanism of GBS in this report. Liver Transpl 12:1537–1539, 2006. © 2006 AASLD.