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Intraoperative blood loss is a risk factor for complications in donors after living donor hepatectomy
Author(s) -
Ibrahim Salleh,
Chen ChaoLong,
Lin ChihChe,
Yang ChinHsiang,
Wang ChihChi,
Wang ShihHo,
Liu YeuhWei,
Yong CheeChien,
Concejero Allan,
Jawan Bruno,
Cheng YuFan
Publication year - 2006
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.20746
Subject(s) - medicine , surgery , hepatectomy , liver transplantation , blood loss , living donor liver transplantation , risk factor , malignancy , transplantation , resection
Abstract Complications in a donor are a distressing but inevitable occurrence, since graft procurement is a major undertaking. Although the technique for procurement has some similarities to hepatic resection, a donor is very unlike a patient with malignancy. The risk factors identified in these patients cannot be extrapolated to donors. Donor hepatectomy carried out from June 1995 to March 2005 in Chang Gung Memorial Hospital, Kaohsiung Medical Center was reviewed with the aim of identifying risk factors for complications. There were 204 living donor liver transplants, with 205 donor hepatectomies, as 1 living donor liver transplantation was a dual graft. Ten donors (4.88%) suffered complications. There was no difference in terms of age, gender, body weight, operation, and parenchymal time between those who had complications and those who did not. There was also no difference in liver function tests between the 2 groups of donors, but the total bilirubin was significantly higher in donors with complications. The graft weight and remnant liver volume were also similar. The proportion of donors with fatty liver was the same between the 2 groups. The mean blood loss in donors with complications was 170 ± 79 mL, and that for donors without complications was 95 ± 77 mL. There was a statistically significant greater blood loss in donors with complications (P < 0.05). The number of segments removed in donors with complications was also higher compared to donors without complications (P < 0.03). Using multivariate analysis, intraoperative blood loss and the number of segments removed were found to be independent risk factors for donor complications. Intraoperative blood loss during graft procurement must be kept low to minimize complications in donors. Liver Transpl 12:950–957, 2006. © 2006 AASLD.