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Use of yttrium‐90 microspheres (TheraSphere®) in a patient with unresectable hepatocellular carcinoma leading to liver transplantation: A case report
Author(s) -
Kulik Laura M.,
Mulcahy Mary F.,
Hunter Russell D.,
Nemcek Albert A.,
Abecassis Michael M.,
Salem Riad
Publication year - 2005
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.20514
Subject(s) - medicine , hepatocellular carcinoma , liver transplantation , liver disease , orthotopic liver transplantation , surgery , adverse effect , carcinoma , stage (stratigraphy) , radiology , transplantation , general surgery , paleontology , biology
Prior to therapy, model for end stage liver disease (MELD) scoring, diagnostic imaging and tumor staging were performed in a patient with T3 HCC. The patient received an orthotopic liver transplant (OLT) 42 days after treatment. The explant specimen showed complete necrosis of the target tumor. Follow‐up of this patient has demonstrated no evidence of recurrence. There was no life threatening or fatal adverse experiences related to treatment. This case report documents the natural course, history and outcome of a patient treated with yttrium‐90 for unresectable HCC. The patient was downstaged from T3 to T2 and was subsequently transplanted. (Liver Transpl 2005;11:1127–1131.)