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Pseudohypocalcemia after magnetic resonance imaging with gadolinium in patients with cirrhosis
Author(s) -
Kefalas Costas H.,
Murray Natalie G.B.,
Aguanno James J.,
Dockery William D.,
Weinstein Jeffrey S.,
Anderson Katherine,
Klintmalm Goran B.
Publication year - 2004
Publication title -
liver transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.814
H-Index - 150
eISSN - 1527-6473
pISSN - 1527-6465
DOI - 10.1002/lt.20008
Subject(s) - gadodiamide , medicine , cirrhosis , magnetic resonance imaging , gadolinium , radiology , differential diagnosis , gastroenterology , pathology , materials science , metallurgy
Abstract Hypocalcemia in patients with cirrhosis may be due to a number of causes. We noted a relationship between injection with gadodiamide, a particular gadolinium chelate, during magnetic resonance imaging of the liver and the development of a falsely low serum total calcium level in a patient with cirrhosis. A cross‐reference and retrospective chart review identified 10 additional patients in whom this phenomenon was noted. We describe the temporal relationship and clinical characteristics of these patients. Pseudohypocalcemia following magnetic resonance imaging with gadodiamide contrast should be considered in the differential diagnosis of hypocalcemia in patients with cirrhosis. (Liver Transpl 2004;10:136–140.)