Comparative Evaluation of 15 Laser and Perfluorodecalin Combinations for Tattoo Removal

Background and Objectives We present a case of laser tattoo removal treated with 15 different combinations using picosecond 1064 nm, picosecond 755 nm, nanosecond 755 nm, and a fractionated CO 2 laser, both with and without a perfluorodecalin (PFD) patch to ascertain the most effective approach. Study Design/Materials and Methods A single lower extremity black tattoo was divided into 15 treatment sections allowing for testing of various laser and PFD combinations. Sectioned treatment was conducted until a treatment superiority was noted. Results After two sessions using sectioned combination treatments with a 4‐week interval clinically significant results were produced. Conclusions The combination of picosecond 1064 nm, picosecond 755 nm, and a fractionated CO 2 laser without the PFD patch showed superior clinical improvement over the other combinations. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.