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Full ablative versus fractional ablative laser therapy for Dowling–Degos disease
Author(s) -
Seitz AnnaTheresa,
Sterz Helen,
Strehlow Vincent,
Nagel Stephanie,
Dumann Konstantin,
Grunewald Sonja,
Simon Jan C.,
Kunz Manfred
Publication year - 2019
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.23021
Subject(s) - ablative case , medicine , abdomen , upper abdomen , laser , ablation , laser therapy , laser ablation , surgery , nuclear medicine , radiology , radiation therapy , optics , physics
Dowling–Degos disease (DDD) is a rare autosomal‐dominant genodermatosis with limited treatment possibilities. Although the efficacy of ablative laser therapy has been reported, we sought to examine the efficacy of fractional versus full ablative laser therapy in a female patient with DDD in a split‐side report. We treated the lesions on the right side of the patient's upper abdomen with an ablative fractional CO 2 laser and the lesions on the left side of the upper abdomen with a full ablative Er:YAG laser (erbium‐doped yttrium aluminium garnet laser) three times at monthly intervals. After three laser sessions, the lesions treated with the Er:YAG laser showed a complete response, whereas the fractional CO 2 laser treatment was less effective. After the three treatments were performed, the right side of the patient's upper abdomen and portions of her lower abdomen and chest were also treated with the Er:YAG laser in full ablation mode with the same settings. After 1 year of follow up, there was no recurrence observed. Lasers Surg. Med. © 2018 Wiley Periodicals, Inc.