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Oncologic results and quality of life in patients with squamous cell carcinoma of hypopharynx after transoral laser microsurgery
Author(s) -
Hung LiTing,
Huang HsinI,
Wang LingWei,
Yang MuhHwa,
Chu PenYuan
Publication year - 2018
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.22742
Subject(s) - medicine , transoral laser microsurgery , microsurgery , quality of life (healthcare) , surgery , basal cell , carcinoma , lymph node , laryngeal neoplasm , larynx , nursing
Objective Transoral laser microsurgery (TLM) is an alternative method for organ preservation in squamous cell carcinoma of hypopharynx (HPSCC). The purpose of this study was to analyze the oncologic results and quality of life (QOL) in HPSCC patients after TLM. Methods Forty‐six patients who underwent TLM were included, 34 of them had QOL evaluations. The QOL analyses were measured with EORTC QLQ‐C‐30, QLQ‐H&N35, VHI‐30, and MDADI at least 6 months postoperatively. Results Most patients were male (96%) with a median age of 60 years. Four patients (9%) were at the T1 category, 24 (52%) at T2, 15 (33%) at T3, and 3 (7%) at T4. Twenty‐nine patients (63%) had cervical lymph node metastases and 26 (57%) received postoperative radiotherapy. With a median follow‐up of 61 months for all patients, 18 (39%) had tumor recurrence, including 4 local, 7 regional, and 7 distant. The 5‐year overall and disease‐specific survival (DSS) rates were 59% and 77%, respectively. The 5‐year laryngeal preservation rate was 89%. Most patients had satisfactory QOLs. Conclusion In early and selective moderately advanced HPSCC, TLM can achieve optimal oncologic results and satisfactory QOL. Lasers Surg. Med. 50:117–124, 2018. © 2017 Wiley Periodicals, Inc.