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Improvement of erythema dyschromicum perstans using a combination of the 1,550‐nm erbium‐doped fractionated laser and topical tacrolimus ointment
Author(s) -
Wolfshohl Jon A.,
Geddes Elizabeth R.C.,
Stout Ashlyn B.,
Friedman Paul M.
Publication year - 2017
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.22567
Subject(s) - medicine , dermatology , ablative case , erythema , tacrolimus , surgery , radiation therapy , transplantation
Background and Objective Erythema dyschromicum perstans (EDP) is a cosmetically distressing, acquired pigmentary disorder of unknown etiology for which few successful therapies exist. Herein, we present the successful use of non‐ablative fractional photothermolysis in combination with topical tacrolimus ointment. Study Design/Patients and Methods A 35‐year‐old female with biopsy‐confirmed EDP underwent a series of fractionated non‐ablative treatment sessions utilizing the 1,550 nm erbium‐doped fiber laser in combination with topical tacrolimus ointment over a period of 5 months. Results The patient's EDP improved by greater than 75% and results were maintained at the 8‐month follow‐up visit. Conclusion The combination of non‐ablative fractional photothermolysis and topical tacrolimus ointment is a potential safe and effective therapeutic option for erythema dyschromicum perstans. Additional prospective, comparative studies are warranted. Lasers Surg. Med. 49:60–62, 2017. © 2016 Wiley Periodicals, Inc.

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