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Ablative fractional laser resurfacing with topical paromomycin as adjunctive treatment for a recalcitrant cutaneous leishmaniasis wound
Author(s) -
Basnett Andrew,
Nguyen Tuyet A.,
Cannavino Christopher,
Krakowski Andrew C.
Publication year - 2015
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.22426
Subject(s) - medicine , paromomycin , surgery , cutaneous leishmaniasis , leishmaniasis , dermatology , wound healing , antibiotics , pathology , aminoglycoside , microbiology and biotechnology , biology
Background and Objective Leishmaniasis is a vector borne disease that can cause disease manifestations that range from localized skin ulceration to lethal visceral disease. With increased global travel, cutaneous leishmaniasis (CL) is becoming more common in developed nations. However, current treatment options are limited. Study Design We report a 16‐year‐old female who presented with several non‐tender, non‐healing CL wounds on her bilateral upper and lower extremities. Ablative fractional laser resurfacing (AFR) was used in conjunction with topical paromomycin via laser‐assisted delivery to treat the largest non‐healing CL wound on the patient's distal lower extremity. Results Upon follow‐up after two treatments with AFR, the patient's wound healed completely without evidence of infection and with minimal scarring. Conclusion AFR with laser‐assisted delivery of topical paromomycin represents a novel treatment option for resistant, non‐healing CL wounds. The technique may prove additionally useful for concurrent mitigation of scarring related to CL. Lasers Surg. Med. 47:788–791, 2015. © 2015 Wiley Periodicals, Inc.