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1064 nm long‐pulsed Nd:YAG laser treatment of basal cell carcinoma
Author(s) -
Ortiz Arisa E.,
Anderson R. Rox,
Avram Mathew M.
Publication year - 2015
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.22310
Subject(s) - medicine , basal cell carcinoma , laser , biopsy , nd:yag laser , trunk , surgery , punch biopsy , adverse effect , carcinoma , ablation , laser treatment , nuclear medicine , basal cell , dermatology , radiology , pathology , optics , ecology , physics , biology
Background and Objective Standard surgical and destructive treatments for basal cell carcinoma (BCC) can result in significant morbidity and scarring, stimulating the investigation of alternative non‐surgical options. The objective of this study was to determine the safety, clinical, and histological efficacy of pulsed, high‐fluence 1064 nm Nd:YAG laser therapy for the treatment of BCC on the trunk and extremities. Study Design/Materials and Methods This was a prospective, non‐randomized, open‐label clinical trial. Ten subjects with a biopsy‐proven BCC less than 1.5 cm in diameter on the trunk or extremities received one treatment with a 10 milliseconds pulsed 1064 nm Nd:YAG laser. Standard excision was performed 1 month after laser treatment to confirm histologic clearance. Results The laser treatment was quick and well tolerated. There was complete histologic clearance after one treatment in 92% of the BCC tumors, overall. At higher fluences, there was 100% histologic clearance after one treatment. No significant adverse events were seen, including scarring. Conclusions The 1064 nm long‐pulsed Nd:YAG laser may offer a safe alternative for treating BCC off the face. A larger study is highly warranted to confirm these preliminary results. Lasers Surg. Med. 47:106–110, 2015. © 2015 Wiley Periodicals, Inc.