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Targeted topical and combination laser surgery for the treatment of angiofibromas
Author(s) -
BaeHarboe YoonSoo Cindy,
Geronemus Roy G
Publication year - 2013
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.22189
Subject(s) - electrosurgery , medicine , dermatology , sirolimus , erythema , ablative case , surgery , lesion , radiation therapy
Background and Objective The angiofibromas of Tuberous sclerosis (TS) is well described manifestation. Due to the progressive nature of the skin lesion, a safe and effective technique for treating these disfiguring skin lesions is needed. Study Design/Patients and Methods We report a targeted topical and combination laser technique for treating the angiofibromas of TS in one patient. This includes treatment with topical sirolimus, pinpoint electrosurgery, pulsed‐dye laser treatment, and ablative fractional resurfacing (AFR). Results Improvement in the number and appearance of facial angiofibromas and erythema is noted, without scarring or adverse events. Conclusion The technique of targeted therapy with sirolimus with electrosurgery, pulsed dye laser treatment, and AFR represents an innovative, safe therapeutic option for treating facial angiofibromas associated with TS. Lasers Surg. Med. 45:555–557, 2013. © 2013 Wiley Periodicals, Inc.